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This strategy not only reduces aggregation risk but also enhances ADC circulation half-life and therapeutic performance

In the efficacy estimand, mean change in body weight at 13 weeks was 5.5% with 60 mg NA-931, 8.7% with the 90 mg dose, 11.3% with 120 mg NA-931, and 13.8% with the 150 mg dose, compared with a 1.9% weight change for placebo

Funding and Disclosures This study was funded by the University of Texas at San Antonio Provosts Undergraduate Research Fellowship

10.1128/IAI.68.4.1942-1945.2000 14 AtliM.ErikogluM.KaynakA.EsenH

Oral supplements must pass through the digestive system, where absorption levels may vary